Which of the following statements with regard to genetic medicine is/are correct ? 1. Genetic medicines correct/compensate for the faulty genes responsible for disease. 2. Engineered viruses and lipid nanoparticles are used as carriers of the genetic medicine. 3. Genetic medicines alter the entire DNA sequence. Select the answer using the code given below :
A
1 only
B
2 and 3 only
C
1 and 2 only
Correct answer
D
1, 2 and 3
Explanation
Genetic medicines such as gene therapies, mRNA and antisense drugs act by correcting, replacing, silencing or compensating for the faulty genes behind a disease. They are delivered by engineered viral vectors (such as AAV or lentivirus) or by lipid nanoparticles. They target specific genes or transcripts and do not rewrite a person's entire DNA sequence, so statement 3 is wrong.
BiotechnologyGenetic medicine and gene therapyGenetic medicineGene therapyViral vectorsLipid nanoparticlesmRNA