In the context of recent advances in human reproductive technology, "Pronuclear Transfer" is used for
A
fertilization of egg in vitro by the donor sperm
B
genetic modification of sperm producing cells
C
development of stem cells into functional embryos
D
prevention of mitochondrial diseases in offspring
Correct Answer
Explanation
Pronuclear Transfer is a key technique in Mitochondrial Replacement Therapy (MRT) used to prevent the transmission of hereditary mitochondrial diseases by transferring the nuclear material of the parents into a donor egg containing healthy mitochondria. While the process occurs during In Vitro Fertilization (IVF), option (a) is incorrect because the technique's specific objective is disease prevention through organelle replacement rather than standard fertilization. The core concept tested is the application of advanced biotechnology in addressing non-nuclear (mitochondrial) genetic inheritance.
BiotechnologyReproductive TechnologyPronuclear TransferHuman reproductive technologyMitochondrial diseasesThree-parent babyIn vitro fertilization