UPSC 2019ScienceModerate

'RNA interference (RNAi)' technology has gained popularity in the last few years. Why? 1. It is used in developing gene silencing therapies. 2. It can be used in developing therapies for the treatment of cancer. 3. It can be used to develop hormone replacement therapies. 4. It can be used to produce crop plants that are resistant to viral pathogens. Select the correct answer using the code given below.

A
1, 2 and 4
Correct Answer
B
2 and 3
C
1 and 3
D
1 and 4 only

Explanation

RNA interference (RNAi) is a biological process where double-stranded RNA molecules inhibit gene expression by neutralizing targeted mRNA, a mechanism used for gene silencing therapies, cancer treatment, and developing virus-resistant crops. Statement 3 is incorrect because RNAi is a "knock-down" technology used to suppress specific proteins, whereas hormone replacement therapy involves supplementing the body with hormones it lacks, which RNAi cannot do. This question tests the core concept of gene silencing and its practical applications in biotechnology and medicine.

BiotechnologyRNA interference (RNAi) applicationsRNA interference (RNAi)gene silencing therapiescancer treatmenthormone replacement therapiescrop plantsviral pathogens

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